Caya Health
1355 South International Parkway, STE 1481, Lake Mary
4.8(411 Google reviews)
Treatment information
Ketamine treatment
A small 2021 randomized controlled trial studied repeated IV ketamine in chronic PTSD. It is useful research, but does not establish long-term effectiveness for all patients or other administration routes. Ketamine treatment for PTSD is off-label; discuss established trauma-focused care and medication options with a qualified clinician.
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Seminole County · Florida
4 listed clinics in Lake Mary. Confirm treatment options and current availability directly with each practice.
Independent directory · confirm services and addresses directly. Educational information, not medical advice.
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Lake Mary, located in Seminole County, is a key residential and commercial hub in Central Florida. For individuals seeking alternative psychiatric interventions such as ketamine or esketamine (Spravato) for severe depression, exploring the Greater Orlando area provides various clinical options to consider.
Residents do not have to travel far to find established mental health clinics offering these treatments. Within Lake Mary itself, Caya Health lists Spravato treatment among its psychiatric services. If you are comparing different approaches, you might also look at nearby Orlando facilities. For instance, Sana Ketamine offers ketamine infusion services, and LifeStance Therapists & Psychiatrists Orlando provides Spravato treatment. Consulting with multiple regional clinics can help you determine the treatment model that aligns with your specific psychiatric needs.
Central Florida’s extensive healthcare network means patients have choices when evaluating care providers. Evaluating different practices ensures you find a setting that matches your clinical requirements. If you are also looking at neighboring communities to compare services or expand your search, you can read our similar localized guides for Apopka and St. Cloud to understand what is available throughout the broader region.
1355 South International Parkway, STE 1481, Lake Mary
4.8(411 Google reviews)
Treatment information
1325 South International Parkway, Suite 2221, Lake Mary
4.9(67 Google reviews)
Cannabis Card Orlando North - Lake Mary is listed in Lake Mary, Florida. The listed appointment address is 1325 S International Pkwy Suite 2221, Lake Mary, FL 32746, USA. Confirm the current location with the practice before travelling.
725 Primera Boulevard, 140, Lake Mary
1.0(3 Google reviews)
Ketamine of Central Florida is listed in Lake Mary, Florida. The listed appointment address is 725 Primera Blvd 140, Lake Mary, FL 32746, USA. Confirm the current location with the practice before travelling.
1325 South International Parkway, ste 2221, Lake Mary
Satori Mental Health - Ketamine Therapy is listed in Lake Mary, Florida. The listed appointment address is 1325 S International Pkwy ste 2221, Lake Mary, FL 32746, USA. Confirm the current location with the practice before travelling.
Treatment schedules vary by clinic and treatment type, so plan transportation for each visit. Distances below are straight-line miles from Lake Mary.
8.3 miles away · Altamonte Springs
222 South Westmonte Drive, Altamonte Springs
5.0(2 Google reviews)
Hue Renew Ketamine Infusions is listed in Altamonte Springs, Florida. The listed appointment address is 222 S Westmonte Dr, Altamonte Springs, FL 32714, USA. Confirm the current location with the practice before travelling.
10.2 miles away · Winter Park
2828 Casa Aloma Way, Suite 200, Winter Park
5.0(24 Google reviews)
Regeneration Medicine of America (Ketamine therapy) is listed in Winter Park, Florida. The listed appointment address is 2828 Casa Aloma Way Ste 200, Winter Park, FL 32792, USA. Confirm the current location with the practice before travelling.
12.4 miles away · Winter Park
1320 South Orlando Avenue, 4, Winter Park
5.0(15 Google reviews)
K+ Clinics Orlando - Ketamine Therapy is listed in Winter Park, Florida. The listed appointment address is 1320 S Orlando Ave 4, Winter Park, FL 32789, USA. Confirm the current location with the practice before travelling.
13.5 miles away · Orlando
15.2 miles away · Orlando
200 East Robinson Street, Unit 425, Orlando
4.6(106 Google reviews)
Treatment information
15.5 miles away · Orlando
6388 Silver Star Road, 2h, Orlando
Freedom Ketamine Treatment Centers is listed in Orlando, Florida. The listed appointment address is 6388 Silver Star Rd 2h, Orlando, FL 32818, USA. Confirm the current location with the practice before travelling.
The administration of IV, IM, or sublingual ketamine for psychiatric conditions like depression is considered off-label. Because it is not FDA-approved for these specific uses, most insurance companies will not cover the cost of the medication or the treatment sessions. Patients are generally responsible for self-paying these expenses. It is highly recommended to request a detailed written estimate outlining the costs for the entire treatment course before beginning. Furthermore, the FDA warns patients and health care providers about potential risks associated with compounded ketamine products.
Unlike off-label ketamine, Spravato (esketamine) is FDA-approved for specific adult depression indications, such as treatment-resistant depression. Therefore, it may be eligible for insurance coverage, though this varies by plan and usually requires a strict prior authorization process. When budgeting for care, remember to factor in the indirect costs of repeated appointments, such as transportation expenses and potential time taken off work during the treatment schedule.
Undergoing ketamine or Spravato therapy requires a significant time commitment, especially during the initial induction phase which involves repeated clinic visits. Spravato must be administered in a certified healthcare setting, followed by at least two hours of clinical observation. Patients are strictly prohibited from driving until the next day, following a restful sleep. A responsible adult must be available to drive you home. When planning your treatments in Central Florida, be mindful that summer heat, severe thunderstorms, and I-4 traffic delays can complicate travel to and from appointments.
While telehealth may be used by clinics to support initial assessments or follow-up consultations, it does not establish home treatment availability. Spravato is never administered at home. Other compounded ketamine formulations are sometimes prescribed off-label by clinicians for at-home use, but they are not FDA-approved for psychiatric care, and the FDA has highlighted serious risks associated with taking these medications without on-site monitoring. For immediate mental health support, contact the 988 Suicide & Crisis Lifeline by calling or texting 988 24/7, or call 911 in emergencies.
No, it is typically considered for adults who have not responded to standard treatments for depression or other specific mental health conditions. A qualified psychiatric provider in Seminole County will review your full medical and psychological history to determine if this therapy is a safe and appropriate choice for you.
IV ketamine is administered intravenously off-label for depression, while Spravato (esketamine) is an FDA-approved nasal spray for specific types of treatment-resistant depression. Spravato is only available at certified clinics, whereas IV ketamine is provided at specialized centers and is typically an out-of-pocket expense.
No, you cannot drive yourself home after receiving either form of treatment. Due to the sedative and dissociative effects, you must have a trusted adult drive you. For Spravato, driving is prohibited entirely until the day following the treatment after a restful night of sleep.
Treatment plans usually require multiple visits over several weeks, especially during the initial induction phase. Providers generally schedule sessions once or twice a week initially. The exact frequency and duration of your plan will depend on your specific condition and response to the medication over time.
Insurance coverage varies significantly. Spravato may be covered for FDA-approved indications if you meet specific criteria, such as trying other antidepressants first. Off-label ketamine infusions are typically not covered and require out-of-pocket payment. Always contact your insurance provider directly for detailed benefits information before scheduling.
Yes. Some clinicians prescribe compounded ketamine for home use, but these medications are not FDA-approved for psychiatric care. The FDA warns about potential risks, including dangerous side effects and a lack of safety monitoring. Additionally, Spravato is strictly prohibited from being administered in any home setting.
Costs, coverage & aftercare
IV, IM and compounded ketamine for psychiatric conditions are off-label; many programs are self-pay. Ask about assessment, medication, administration, monitoring, therapy and maintenance charges separately. We do not assume a statewide price.
Spravato is FDA-approved esketamine, not the same as ketamine infusions. Coverage is not guaranteed. Check eligibility, prior authorization, network status, drug and visit charges, deductibles and copays with your insurer and clinic.
Spravato requires a certified healthcare setting and monitoring for at least two hours. Arrange transport home; do not drive until the next day after restful sleep. For other ketamine treatments, follow your clinician's instructions. Follow-up and maintenance depend on response and tolerability.
Ask who manages your medications, how your usual clinician will receive updates, and whom to contact between visits. Neither a shortage designation nor local depression statistics show that ketamine is appropriate or effective for you. Consult a licensed physician.
Use these questions when you call or book a consultation with any Lake Mary provider.
Ask whether a physician, psychiatrist or anesthesiologist oversees each session and who you can reach afterward.
A good clinic reviews your history, medications, blood pressure and past treatments before recommending ketamine.
Look for continuous vital-sign monitoring and a calm, private recovery space.
IV infusions, Spravato® nasal spray, IM or sublingual options suit different goals and budgets.
Ask how the clinic coordinates with your therapist or offers integration support between sessions.
Request a written estimate for the first series and any maintenance sessions before you start.
| Clinic | Google rating | Reviews | Phone |
|---|---|---|---|
| Caya HealthLake Mary | 4.8 | 411 | (407) 559-7011 |
| LifeStance Therapists & Psychiatrists OrlandoOrlando | 4.6 | 106 | (407) 787-9777 |
| Cannabis Card Orlando North - Lake MaryLake Mary | 4.9 | 67 | (321) 392-6420 |
| Regeneration Medicine of America (Ketamine therapy)Winter Park | 5 | 24 | (407) 986-4325 |
| K+ Clinics Orlando - Ketamine TherapyWinter Park | 5 | 15 | (850) 495-7587 |
| Sana KetamineOrlando | 5 | 8 | (407) 801-1084 |
| Ketamine of Central FloridaLake Mary | 1 | 3 | (407) 732-7266 |
| Hue Renew Ketamine InfusionsAltamonte Springs | 5 | 2 | (407) 305-4773 |
Ratings come from public Google reviews and change over time. Listing order is not a medical recommendation.
Many patients travel a short distance for a clinic that fits their needs. Explore ketamine care in these nearby communities.
Browsing a wider area? See every clinic in Seminole County
Conditions Ketamine treats, county-wide options and guides written for Florida patients.